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: Some evidence indicates it may be "possibly effective" for improving mood in people with low DHEA levels, though it is not a first-line therapy.

DHEA is most effective when treating documented hormone deficiencies or specific medical issues rather than as a general wellness supplement: buy dhea supplement

: It is "likely effective" for treating thinning vaginal tissue (vaginal atrophy) in postmenopausal women. FDA-approved vaginal inserts are available for this purpose. : Some evidence indicates it may be "possibly

: In women with diminished ovarian reserve, some studies suggest DHEA may improve egg quality, increase pregnancy rates, and lower miscarriage risks when taken under medical supervision for 6–12 weeks before IVF. : In women with diminished ovarian reserve, some

Because DHEA is a hormone, quality control is critical. Over-the-counter (OTC) products often vary significantly in potency, sometimes containing 0% to 150% of the labeled amount. DHEA - Mayo Clinic