: Obstruction causes a ventilation-to-perfusion ( ) mismatch, leading to hypoxemia and respiratory distress. Diagnostic Framework
: For high-risk (hemodynamically unstable) patients, systemic thrombolysis (e.g., Alteplase) is recommended to rapidly dissolve the clot. Download Embolie pulmonaire aiguГ« pdf
: Tools such as the Wells Score or Geneva Score assess pre-test probability. The PERC (Pulmonary Embolism Rule-out Criteria) is used to safely exclude PE in low-risk patients without further testing. systemic thrombolysis (e.g.
The development of PE is governed by , which consists of venous stasis, endothelial injury, and a hypercoagulable state. which consists of venous stasis
: Once a clot lodges in the pulmonary vascular bed, it increases pulmonary vascular resistance, which can lead to acute right ventricular (RV) failure and hemodynamic collapse.