Following the death of his previous partner, Juzo Biwa, Itachi is paired with Kisame Hoshigaki . Their initial meeting is tense but marked by mutual respect for their "ninja-slayer" reputations.

The definitive moment showing why Orochimaru feared Itachi and eventually shifted his focus toward Sasuke. 💡 Why It Matters

A short but iconic fight that establishes Itachi's overwhelming visual prowess.

While Itachi carries out missions, his thoughts remain tethered to the Hidden Leaf and his younger brother, Sasuke .

This episode bridges the gap between Itachi’s defection and his first appearance in the original Naruto series. It humanizes him by showing his internal isolation even while surrounded by the world's most dangerous criminals. A breakdown of the Itachi used on Deidara? Which filler episodes you can skip after this arc?