After reclaiming his role as Head of Diagnostics, House attempts to rebuild his fractured team by preying on the insecurities of his former fellows. He doesn't seek a harmonious unit; he seeks tools to solve a complex case involving a porn star with pulsating eye pain.
"Teamwork" suggests that in House’s world, a team is not a supportive community but a machine that requires individual sacrifices to function. It poses the "interesting" question: is a team truly successful if it solves the case but destroys the lives of its members in the process?
: Cameron eventually leaves, not just because of the medical risks House takes—like "nuking" a patient's bone marrow—but because she realizes the "team" is a toxic environment that has fundamentally changed Chase.
The episode highlights a fundamental tension between individual morality and the team's objective. This is most visible in the character of Cameron, who serves as the episode's moral compass, albeit a polarizing one.