Under E6 May 2026
Code of Criminal Procedure, 1898
Code of Criminal Procedure, 1898 is the main legislation on procedure for administration of substantive criminal law in Pakistan. It provides the machinery for the investigation of crime, apprehension of suspected criminals, collection of evidence, determination of guilt or innocence of the accused person and the determination of procedure. It extends to the whole of, Pakistan but, in the absence of any specific provision to the contrary, nothing therein contained shall affect any special or local law, new in force, or any special jurisdiction or power conferred or any special form of procedure prescribe by any other law for the time being in force.
Under E6 May 2026
For the first time, the guideline explicitly addresses digital tools, wearables, and the "chain of custody" for digital data to ensure traceability and reproducibility.
Monitoring and oversight are now scaled based on the actual risks of a trial. Low-risk aspects should not be overburdened with unnecessary bureaucracy. under e6
E6(R3) emphasizes building quality into the trial design from the start, rather than relying on retrospective checking. For the first time, the guideline explicitly addresses
There is a renewed focus on patient well-being, including expanded transparency in informed consent (e.g., explaining what happens to data if a participant withdraws). 2. OfS Condition E6: Higher Education Safety Quality by Design in Clinical Trials under ICH E6(R3) E6(R3) emphasizes building quality into the trial design
The International Council for Harmonisation (ICH) recently finalized the guideline, which entered into force in July 2025. This update represents a major shift toward digital-first, risk-proportional clinical research.
